Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf8  fibroblast growth factor 8   (Synonyms: Aigf, Fgf-8)
Results	Reference
1	J:53300 Acampora D, Simeone A, The TINS Lecture. Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis. Trends Neurosci. 1999 Mar;22(3):116-22
1*	J:236309 Aires R, Jurberg AD, Leal F, Novoa A, Cohn MJ, Mallo M, Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity. Dev Cell. 2016 Aug 8;38(3):262-74
1	J:313582 Anderson MJ, Magidson V, Kageyama R, Lewandoski M, Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function. Elife. 2020 Nov 19;9:e55608
1	J:98791 Blak AA, Naserke T, Weisenhorn DM, Prakash N, Partanen J, Wurst W, Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse. Dev Dyn. 2005 Apr 13;233(3):1023-1030
1	J:299537 Boylan M, Anderson MJ, Ornitz DM, Lewandoski M, The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall. Development. 2020 Oct 19;147(21):dev189506
1	J:36587 Bueno D, Skinner J, Abud H, Heath JK, Spatial and temporal relationships between Shh, Fgf4, and Fgf8 gene expression at diverse signalling centers during mouse development. Dev Dyn. 1996 Nov;207(3):291-9
1	J:124082 Cambray N, Wilson V, Two distinct sources for a population of maturing axial progenitors. Development. 2007 Aug;134(15):2829-40
1	J:269325 De Castro SCP, Gustavsson P, Marshall AR, Gordon WM, Galea G, Nikolopoulou E, Savery D, Rolo A, Stanier P, Andersen B, Copp AJ, Greene NDE, Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice. Hum Mol Genet. 2018 Dec 15;27(24):4218-4230
1*	J:46975 Ericson J, Norlin S, Jessell TM, Edlund T, Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development. 1998 Mar;125(6):1005-15
1	J:270575 Mastromina I, Verrier L, Silva JC, Storey KG, Dale JK, Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse. Development. 2018 Jul 30;145(14):dev161091
1*	J:96484 Molotkova N, Molotkov A, Sirbu IO, Duester G, Requirement of mesodermal retinoic acid generated by Raldh2 for posterior neural transformation. Mech Dev. 2005 Feb;122(2):145-55
1	J:89798 Momoi T, Fujita E, Urase K, Strain-specific caspase-3-dependent programmed cell death in the early developing mouse forebrain. Neuroreport. 2003 Jan 20;14(1):111-5
1	J:215128 Moon AM, Stauffer AM, Schwindinger WF, Sheridan K, Firment A, Robishaw JD, Disruption of G-protein gamma5 subtype causes embryonic lethality in mice. PLoS One. 2014;9(3):e90970
1	J:206578 Nonomura K, Yamaguchi Y, Hamachi M, Koike M, Uchiyama Y, Nakazato K, Mochizuki A, Sakaue-Sawano A, Miyawaki A, Yoshida H, Kuida K, Miura M, Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells. Dev Cell. 2013 Dec 23;27(6):621-34
1	J:119303 Seo S, Kume T, Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract. Dev Biol. 2006 Aug 15;296(2):421-36
1	J:217059 Takemoto T, Uchikawa M, Yoshida M, Bell DM, Lovell-Badge R, Papaioannou VE, Kondoh H, Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells. Nature. 2011 Feb 17;470(7334):394-8
1*	J:74631 Tian E, Kimura C, Takeda N, Aizawa S, Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
1	J:105216 Trokovic N, Trokovic R, Partanen J, Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm. Int J Dev Biol. 2005;49(7):797-805
1*	J:160266 van Bueren KL, Papangeli I, Rochais F, Pearce K, Roberts C, Calmont A, Szumska D, Kelly RG, Bhattacharya S, Scambler PJ, Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome. Dev Biol. 2010 Apr 15;340(2):369-80
1*	J:219234 Wang J, Rhee S, Palaria A, Tremblay KD, FGF signaling is required for anterior but not posterior specification of the murine liver bud. Dev Dyn. 2015 Mar;244(3):431-43
1	J:106144 Ware SM, Harutyunyan KG, Belmont JW, Zic3 is critical for early embryonic patterning during gastrulation. Dev Dyn. 2006 Mar;235(3):776-85
1*	J:56088 Xu J, Lawshe A, MacArthur CA, Ornitz DM, Genomic structure, mapping, activity and expression of fibroblast growth factor 17. Mech Dev. 1999 May;83(1-2):165-78
1	J:61429 Xu J, Liu Z, Ornitz DM, Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures. Development. 2000 May;127(9):1833-43
1	J:243036 Zhang R, Cao P, Yang Z, Wang Z, Wu JL, Chen Y, Pan Y, Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling. PLoS One. 2015;10(8):e0136518
1	J:112457 Zhang Z, Huynh T, Baldini A, Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development. Development. 2006 Sep;133(18):3587-95
1	J:87046 Zoltewicz JS, Stewart NJ, Leung R, Peterson AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14